Wogonin and neobaicalein from Scutellaria litwinowii roots are apoptotic for HeLa cells
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چکیده
منابع مشابه
Analyzing Cytotoxic and Apoptogenic Properties of Scutellaria litwinowii Root Extract on Cancer Cell Lines
The Scutellaria species (Lamiaceae) is used as a source of flavonoids to treat a variety of diseases in traditional medicine. In spite of many reports about the cytotoxic and antitumor effects of some species of this genus, anticancer researches on one of the Iranian species S. litwinowii have not yet been conducted. The cytotoxic properties of total methanol extract of S. litwinowii and its fr...
متن کاملHigh-yield Production of Scutellaria Radix Flavonoids (Baicalein, Baicalin and Wogonin) by Liquid-culture of Scutellaria baicalensis Root-derived Cells
Production of baicalein, baicalin and wogonin by liquid culture of Scutellaria baicalensis cells derived from the plant root was studied. The maximum production obtained were 119 mg/L of baicalein at two week, 1372 mg/L of baicalin at eight week, and 14 mg/L of wogonin at two week. In addition, the production of baicalin was drastically increased to 1000 mg/L level at 3-week culture, and the ex...
متن کاملQuantification of propionic acid from Scutellaria baicalensis roots
BACKGROUND Propionic acid is a widely used preservative and has been mainly formed by artificial synthesis or fermentation. In the case of natural products, the presence of propionic acid is viewed as a sign that an additive has been introduced for antimicrobial effects. METHODS In this work, the propionic acid that occurs in Scutellaria baicalensis roots was studied. A quantification method ...
متن کاملSkullcap (Scutellaria baicalensis) extract and its active compound, wogonin, inhibit ovalbumin-induced Th2-mediated response.
Skullcap (Scutellaria baicalensis) has been widely used as a dietary ingredient and traditional herbal medicine owing to its anti-inflammatory and anticancer properties. In this study, we investigated the anti-allergic effects of skullcap and its active compounds, focusing on T cell-mediated responses ex vivo and in vivo. Splenocytes from mice sensitized with ovalbumin (OVA) were isolated for a...
متن کاملWhat HeLa Cells Are You Using?
The HeLa cell line, named after the patient Henrietta Lacks, was one the first human cell lines to be used for tissue culture. In the decades since its origin, it has become a feature in labs across the world. Despite its longevity, repeated detection of most HeLa marker chromosomes have lead the scientific community to view HeLa as a stable cell line and its corresponding findings to be reprod...
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ژورنال
عنوان ژورنال: Revista Brasileira de Farmacognosia
سال: 2012
ISSN: 0102-695X
DOI: 10.1590/s0102-695x2011005000161